Science at the Heart of Medicine
At Montefiore Einstein Comprehensive Cancer Center we believe in a research-focused, evidence-based approach to cancer care. Our patients have access to world-renowned cancer specialists and groundbreaking treatments—thanks to the strength of our research enterprise.
We’re involved in more than 300 cancer clinical trials, and our discovery-driven environment is a place where research trainees and professionals thrive.
Depending on the stage and diagnosis of a patient’s cancer, clinical trial participation may be an option. Investigators at Montefiore Einstein Comprehensive Cancer Center are involved in numerous clinical trials—from interventional trials to observational and feasibility studies.
Programas de investigación transdisciplinaria
Innovation happens when we bring together different insights, approaches and perspectives.
Nuestros programas de investigación transdisciplinaria reúnen a científicos de laboratorio y médicos-científicos de renombre internacional de diversos campos académicos para colaborar en investigación básica, traslacional y clínica. Cada investigador aporta su experiencia y perspectiva únicas al desarrollo de nuevos diagnósticos y tratamientos para personas con cáncer.
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Tumor Microenvironment and Metastasis
brings together advanced in vivo imaging technologies and innovative animal models to examine how the tumor microenvironment prompts and sustains cancer spread. The goal is to identify novel biomarkers and treatment targets that will aid in personalizing the prevention and treatment of metastases.
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Stem Cell and Cancer Biology
encompasses three interrelated themes: How healthy stem cells function and prevent cancer formation; the characterization of healthy and cancerous stem cells in patients in order to develop novel diagnostics and treatment; and the biochemical and molecular mechanisms behind gene regulation, RNA translation, and splicing that drives stem cell differentiation.
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Tratamiento contra el cáncer
provides oversight for all clinical therapeutic trials at our Cancer Center and the development of novel therapies based on our scientists’ basic laboratory discoveries. The program is the focal point for developing small molecule inhibitors and novel immunotherapies for the treatment of cancer.
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Cancer Epidemiology, Prevention and Control
reflects the expanded scope of population-based research that examines infectious, metabolic, endocrine, obesity-related and genetic/epigenetic causes of cancer and their prevention and control.
Institutos e Iniciativas de Investigación Básica y Traslacional
At Montefiore Einstein Comprehensive Cancer Center, we focus on multiple facets of oncology research in our drive to better understand cancer and improve care. The more we learn, the better equipped we and others are to develop new diagnostic tests, preventive care plans and targeted, personalized treatments.
To create innovative cancer treatment strategies, we study solutions through:
- Investigación básica: mediante la investigación básica de laboratorio, nuestros científicos investigan aspectos fundamentales, como los factores genéticos y ambientales que propician la aparición y propagación del cáncer. La investigación básica nos ayuda a comprender o profundizar nuestros conocimientos sobre el funcionamiento de las células y los sistemas corporales.
- Translational research. Here’s where we turn basic discoveries in the lab into useful tools and treatments for cancer and acquire a deeper understanding of cancer risk and incidence across populations.
Much of this research is accomplished through the work of investigators in our Transdisciplinary Research Programs, as well as through various Montefiore Einstein institutes and initiatives such as:
- Cáncer de mama
ENSAYO I-SPY: nuevos agentes adaptativos personalizados y neoadyuvantes para tratar el cáncer de mama
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Afecciones
Cáncer de mama
- Multiple Hematologic Malignancies
A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects with Relapsed/Refractory Hematologic Malignancies
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Afecciones
Multiple Hematologic Malignancies
- Chronic Lymphocytic Leukemia
- Diffuse Large B-Cell Lymphoma
- Acute Lymphocytic Leukemia
Phase I/II Study of Rapcabtagene Autoleucel in CLL/SLL, 3L DLBCL, R/R ALL and 1L HR LBCL
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Afecciones
Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma; Acute Lymphocytic Leukemia
- Cáncer endometrial
Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment with the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers
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Afecciones
Cáncer endometrial
- Limited-Stage Small-Cell Lung Cancer
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)
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Afecciones
Limited-Stage Small-Cell Lung Cancer
- Multiple
Study to Investigate the Efficacy, Safety, and Tolerability of Topical HT-001 for the Treatment of Skin Toxicities Associated With Epidermal Growth Factor Receptor Inhibitors
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Afecciones
Multiple
- Lung Cancer
Study to Assess Neoadjuvant Durvalumab (D) and Platinum-Based Chemotherapy (CT), Followed by Either Surgery and Adjuvant D or CRT and Consolidation D, in Resectable or Borderline Resectable Stage IIB-IIIB NSCLC (MDT-BRIDGE)
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Afecciones
Lung Cancer
- Urothelial/Bladder Cancer
Study of BT8009 as Monotherapy or in Combination in Participants with Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)
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Afecciones
Urothelial/Bladder Cancer
Montefiore Einstein Comprehensive Cancer Center Shared Resources
Successful translational research requires a multidisciplinary approach. At Montefiore Einstein Comprehensive Cancer Center, we support the sharing of clinical, basic science and epidemiology expertise in the name of fostering new ways to better diagnose, treat and prevent cancer.
Our state-of-the-art technology, facilities and support services give our research teams everything they need to investigate cancer development, prevention and treatment.
We provide our world-renowned specialists, researchers and scientists with the resources they need to succeed, including partnerships with the postdoctoral fellows and researchers at the Albert Einstein College of Medicine.
Research Training Programs
As part of the Albert Einstein College of Medicine, our research teaches and trains the next generation of cancer research leaders. We offer a Ph.D program and a Medical Scientist Training Program (MSTP). Students gain exposure to biomedical research lab work, clinical pathology and more. And Einstein’s Belfer Institute for Advanced Biomedical Studies functions to help integrate all of the college’s postdoctoral training programs, serving as an advocate for trainees at this stage.
- Learn about our Ph.D program
- Learn about our Medical Scientist Training Program
- Learn about the Belfer Institute for Advanced Biomedical Studies
Professional Development and Educational Opportunities
We’re committed to helping cancer clinicians and researchers grow professionally and advance in their fields. Learn about our extensive cancer research education and training programs for students and professionals.
Noticias breves
Breakthrough Discovery Overturns Long-Held Belief About Blood Stem Cells
Comunicado de prensa
Britta Will, Ph.D., Named Director of Gottesman Institute for Stem Cell Research and Regenerative Medicine
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More than 130 bench scientists and clinical researchers work in cancer discovery.
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