Centro Montefiore Einstein para la Investigación del Autismo y los Trastornos de la Comunicación

Leading-Edge Autism & Communication Disorder Research

The Montefiore Einstein Center for Autism and Communications Disorders’ extensive research partnerships and initiatives have established Montefiore Einstein as leading stewards of the latest diagnostic, psychological and neuropsychological evaluations and treatments for people ages 5+ who face autism spectrum disorders and other developmental disabilities.

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Proyectos actuales

The Center for Autism and Communications Disorders hosts multiple initiatives to help patients, families, and caregivers navigate the challenges of living with or caring for someone with a developmental disorder. Our programs include the following:

Programa CAAPABLE

Un componente central de CAAPABLE es el Proyecto Prosodia, que ayuda al desarrollo del acento y la entonación en el habla, así como a la comunicación no verbal, como el uso de los ojos y los gestos. La prosodia deteriorada es uno de los obstáculos más importantes para la integración social y profesional.

Proyecto Prosodia

El Proyecto Prosodia desarrolla el timbre vocal y la prosodia verbal (melodía, volumen, ritmo y fluidez del habla) y no verbal (uso de los ojos, gestos) en adolescentes y adultos con trastorno del espectro autistas (TEA). Lamentablemente, la prosodia deficiente puede desempeñar un papel importante en la formación de una primera impresión negativa. Como resultado, los dones y las contribuciones potenciales de las personas con déficits de prosodia a menudo pasan desapercibidos. La prosodia deficiente es, de hecho, uno de los obstáculos más importantes para la “integración social y la aceptación profesional”.

Dunn, MA y Harris, LE (en prensa). La música del habla: Intervención prosódica para adolescentes de alto funcionamiento con trastornos del espectro autista . Londres: Jessica Kingsley Publishers.

Sensory Integration Therapy in Autism: Mechanisms and Effectiveness

A common feature of ASD is over or under sensitivity to the environment and difficulty putting sensory information together in an orderly way, referred to here as sensory issues. Building on previous work, this study will test the efficacy of Sensory Integration Therapy (SIT), a non-invasive intervention to improve functional skills in children with ASD, in comparison to commonly applied ABA behavioral treatments, in the treatment of ASD symptoms.

A 12-week Placebo-Controlled Study to Investigate the Efficacy, Safety and Tolerability of RO7017773 in Participants Aged 15 - 45 years with Autism Spectrum Disorder (ASD)

This study will investigate the efficacy, safety, tolerability, and pharmacokinetics of RO7017773 in participants aged 15-45 years who have been diagnosed with ASD with a score of >/=50 on the Wechsler Abbreviated Scale of Intelligence (WASI-II).

Voxelator Neurocognitive Function Study

This is a Phase 3b, randomized, double-blind, placebo-controlled, multicenter study to assess the treatment effect of voxelotor on neurocognitive function as assessed by the National Institute of Health (NIH) Toolbox Cognition Module of executive abilities in pediatric participants (8 to < 18 years) with SCD.

An Open-Label Study of CM-AT for the Treatment of Children with Autism

This is a Phase III, open label extension study evaluating the continued safety and efficacy of CM-AT in pediatric patients with autism with all levels of fecal chymotrypsin.

Our Collaborators

Our program actively collaborates with the Montefiore Einstein Institute for Clinical and Translational Research (ICTR) and other clinical investigators at Montefiore Einstein. We have received funding from the following organizations:

Illustration of two lab technicians holding test tubes standing in front of a wall with multitude of lab samples illustrations.

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