The Montefiore Einstein Neuroscience Center is internationally recognized as one of the most comprehensive, innovative and advanced centers of its kind. Our center continues to elevate the standard for biomedical creativity and discovery established by our visionary founders, who defined major new fields of interdisciplinary scholarship that have progressively expanded the scope of what encompasses modern neuroscience disciplines today, giving rise to explosive new understandings of disease mechanisms that led to disease-modifying therapies and eventual cures.
Changing Lives through Unprecedented Innovation
Setting the Standard for New Neuroscience Discoveries & Advanced Treatment Strategies
At Montefiore Einstein, we bring together our culture of explosive innovation including basic, translational and clinical research breakthroughs to advance our understanding of the nervous system across a wide range of closely interrelated research areas of neuroscience including cellular and molecular, systems biology, developmental, cognitive and behavioral, bioinformatics/AI, and clinical. Our unique collaborative and interdisciplinary study of the nervous system has led to notable groundbreaking discoveries, some of which include that the peripheral nervous system gives rise to cancer and metastases, and that the brain is the seat of longevity and the key player in regulating glucose metabolism in diabetes.
Distinguished by Unmatched Interdisciplinary Collaboration
Our world-renowned interdisciplinary clinical, diagnostic and therapeutic specialists, physician-scientists, as well as associated scientists from the departments of Neuroscience, Neurology, Neurosurgery, Psychiatry & Behavioral Sciences, Neuro-Radiology and Rehabilitation Medicine. Our teams also encompass a wide spectrum of basic science disciplines including genomics, stem cell biology, systems and computational/AI biology, bioengineering, developmental biology, biochemistry, and structural biology. We approach neuroscience through a wide and diverse lens of expertise, and remain at the forefront of research offering patients life-changing solutions to protect, preserve and restore neurological function, and enhance brain resilience.
Changing What’s Possible
Our Latest Research
Advancing human health, scientific discovery and innovation through neurological research.
Leaders in the Science of Neurological Care
At the Montefiore Einstein Neuroscience Center, we are committed to applying the latest biomedical breakthroughs and technological innovations to advance our understanding of the underlying mechanisms mediating the full spectrum of neurological disorders. Our development of revolutionary diagnostic and treatment paradigms to prevent, delay, ameliorate and eventually cure diseases that are frequently chronic and debilitating, and provides hope and inspiration to patients, families and interconnected communities.
We are at the forefront of numerous advanced NIH-funded translation research initiatives, and associated clinical trials, to advance treatments of targeted neurological diseases, including: early detection and prevention of Alzheimer’s disease and pre-dementia syndromes; post-traumatic epilepsy; brain health and resilience during aging; neuroprotective and neuroregenerative strategies to promote healthy brain function, as well as defining the broad and complex neurologic and systemic effects of SARS-CoV-2/COVID-19 following acute and chronic infection.
State-of-the-Art Technology
We utilize the most advanced techniques available today, including sophisticated neuroimaging (scaling from newly emerging nanotechnology to multimodal whole-brain paradigms), and genomics/epigenomics, as well as AI and machine learning, to help implement new treatments and improve clinical outcomes for those with nervous system disorders.
Committed to Closing the Gap between Neurological Disease & Brain Health
Meet Your Neuroscience Center Team
Montefiore Einstein’s Neuroscience Center is led by four world-renowned leaders who are recognized for their vision, expertise, and innovations across neuroscience. Together, they lead a nationally and internationally renowned interdisciplinary team dedicated to changing the lives of each individual patient.
From Left to Right: Mark F. Mehler, MD (Chair, The Saul R. Korey Department of Neurology); Adam Kohn, PhD (Interim Chair, Dominick P. Purpura Department of Neuroscience); Jonathan E. Alpert, MD, PhD (Dorothy and Marty Silverman Chair in Psychiatry); Emad N. Eskandar, MD (Jeffrey P. Bergstein Chair in Neurological Surgery, The Leo M. Davidoff Department of Neurological Surgery)
- Multiple Sclerosis
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis
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Start Date
March 10, 2023
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Conditions
Relapsing Multiple Sclerosis
- Migraine
A Phase 2/3 Randomized, Double-Blind, Placebo- Controlled Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention
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Start Date
February 3, 2021
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Conditions
Migraine
- Migraine
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
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Start Date
February 28, 2022
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Conditions
Migraine
- Focal Onset Seizures
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures
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Start Date
November 18, 2022
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Conditions
Focal Onset Seizures