Paul Koors, MD,
Aortic Clinic
Paul Koors, MD, Aortic Clinic
Paul Koors, MD
A devoted husband, son, father, musician, doctor, and friend, Dr. Paul Koors touched countless lives throughout his too short yet inspiring life. As a young man, Paul gained an interest in medicine at Montefiore, where his mother, Dr. Patricia McQuade-Koors, committed her 50-year-long career as a pediatrician. Montefiore Einstein holds special meaning to the Koors family.
To deepen Paul’s impact and extend his legacy, please consider contributing to the Paul Koors, MD, Aortic Clinic at Montefiore Einstein. Since its inception in 2021, the Aortic Clinic has become an indispensable resource, playing a pivotal role in diagnosing and treating a wide range of aortic complications like Marfan syndrome and aortic dissection, the condition that took Paul’s life. The clinic’s more recent efforts have shifted toward better understanding the genomics of aortic disease, which will enable physicians to make earlier diagnoses, offer more robust treatment options, and share their knowledge.
For more information, please contact:
Kristen Kidder
Assistant Vice President, Development
Montefiore Einstein
718-430-2412 | kristen.kidder@einsteinmed.edu
With partners like you and the Paul Koors Memorial Foundation, Montefiore Einstein is poised to make significant strides in genomics research, physician training, and community education.
Next-Generation
Collaborative Research
The Aortic Clinic is home to the Montefiore Einstein Aortic Disease Research and Education Initiative (ADREI). Among ADREI’s most cutting-edge interventions in genomics and aortic disease are investigations into the non-coding genome—the 98 percent of our DNA that is not the genes themselves. A team jointly led by Joseph DeRose, MD, Professor of Cardiothoracic & Vascular Surgery, and John Greally, DMed, MB, BCh, BAO, PhD, Professor of Genetics and Pediatrics, Chief of the Division of Genomics, Executive Director of the New York Center for Rare Diseases, and Director of the Center for Epigenomics, is developing both DNA sequencing technology and computational analytical approaches to interpret changes to that part of the genome.
To better understand the cells involved in aortic disease, investigators often study aortic tissue removed during surgery. Drs. DeRose and Greally are collecting samples from the operating room and analyzing them using advanced DNA sequencing tools. The team’s goal is to improve diagnosis and treatment by defining the damage to non-coding DNA that causes thoracic aortic diseases.
Joseph DeRose, MD
John Greally, DMed, MB, BCh, BAO, PhD
Outreach to Clinical Colleagues
Recognizing the importance of education and advocacy in advancing the field, Drs. DeRose and Greally host regular “Aortic Dinners,” a key initiative within ADREI that brings together experts to share our vital work and promote awareness. By highlighting new developments and discussing the implications for patient care, we aim to inspire collaborative efforts that will lead to improved outcomes for those affected by this life-threatening condition.