Peyronie’s Disease

At Montefiore Einstein Urology, you can access exceptional care for Peyronie’s disease. As a global leader in urology, we are an academic-based, national and international referral site for the most complex and high-risk cases. For more than a century, we have been at the forefront of innovation, research and clinical care for genitourinary (GU) conditions.

Ranked in the top 1% of all hospitals in the nation for urology according to U.S. News & World Report, Montefiore Einstein continues to make advances in the diagnosis and treatment of GU conditions. Our multidisciplinary team of world-renowned specialists is passionate about uncovering the latest diagnostic approaches and treatments that can improve outcomes.

At Montefiore Einstein Urology, you can expect compassionate, personalized, research-driven treatment plans that meet the highest standards for quality and safety. In addition, we offer patients a full range of support services, from nutritional guidance to rehabilitative therapies. We also performed the world’s first successful penile plaque excision and xenografting procedure using Kerecis fish skin for Peyronie’s disease.

When you need Peyronie’s disease care, turn to our dedicated multidisciplinary team for a personalized treatment plan.

Montefiore Einstein offers the following content from Healthwise’s health information library.

What Is Peyronie’s Disease?

Peyronie’s disease is a condition which causes scar tissue, known as plaque, to form under the skin of the penis. As this plaque develops, it pulls on the surrounding tissues causing the penis to curve or bend, usually during an erection. Curves in the penis can lead to painful erections and difficulty maintaining erection during sexual intercourse.

Causes of Peyronie’s Disease

The exact cause of Peyronies disease is unknown, but possible factors that may contribute to its development are:

  • Acute or chronic injury to the penis
  • Autoimmune disease

Signs & Symptoms of Peyronie’s Disease

Symptoms of Peyronie’s disease include:

  • A change in the shape of the penis
  • A curve in the penis
  • Erectile dysfunction
  • Hard lumps on the side of the penis
  • Pain during sexual intercourse or during an erection

These may develop slowly or quickly and can be mild to severe. In many cases, the pain decreases over time, although the curve in the penis may remain.

Diagnosing Peyronie’s Disease

Specialized urologists typically diagnose Peyronie’s disease through a comprehensive physical examination and evaluation of the patient’s medical history. 

Treating Peyronie’s Disease

The treatment goal for Peyronie’s disease is to reduce pain, reduce curves in the penis and restore and maintain the ability to have sexual intercourse. We provide several nonsurgical and surgical treatments, depending on the severity of symptoms and whether the disease is acute or chronic. Treatments include:

  • Injections: For patients with acute Peyronie’s disease, intralesional injections are administered directly into the plaque and are provided in the doctor’s office.  
  • Oral medicines: At this time, there are no oral medicines that effectively treat penile curvature. Potassium para-aminobenzoate is used to treat Dupuytren’s contracture and may reduce plaque size, but it has no effect on penile curving.
  • Surgery: Surgical treatments, including grafting, plication and device implantation can be used to remove plaque or help straighten the penis during an erection. Surgery for Peyronie’s disease may be recommended for patients whose symptoms have not improved after being treated with less invasive solutions and for those who experience pain during erection or intercourse. Surgery may also be recommended when the curve in the penis prevents sexual intercourse.

Physician Referrals

Montefiore Einstein embraces a collaborative approach. 
If you have a patient who could benefit from our services, please reach out.